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Microorganisms
may be protected from
disinfectants by production of thick
masses of cells and extracellular materials, or biofilms.
Biofilms are microbial communities that are tightly
attached to surfaces and cannot be easily removed. Once
these masses form, microbes within them can be resistant
to disinfectants by multiple mechanisms, including
physical characteristics of older biofilms, genotypic
variation of the bacteria, microbial production of
neutralizing enzymes, and physiologic gradients within
the biofilm (e.g., pH). Bacteria within biofilms are up
to 1,000 times more resistant to antimicrobials than are
the same bacteria in suspension. Although new
decontamination methods are being investigated for
removing biofilms, chlorine and monochloramines can
effectively inactivate biofilm bacteria. Biofilms have
been found in whirlpools, dental unit waterlines, and
numerous medical devices (e.g., contact lenses,
pacemakers, hemodialysis systems, urinary catheters,
central venous catheters, endoscopes). Their presence
can have serious implications for immune-compromised
patients and patients who have indwelling medical
devices. Some enzymes and detergents can degrade
biofilms or reduce numbers of viable bacteria within a
biofilm, but no products are EPA-registered or
FDA-cleared for this purpose. See also
Bioburden.
See the
complete recommendations on sterilizer and disinfection
at
www.cdc.gov
“Guideline for Disinfection and Sterilization in
Healthcare Facilities, 2008”. |
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DID YOU KNOW?
§
Autoclave Testing Service, Inc. is one of the first
companies nationwide to offer a
Mail-In
sterilizer monitoring service using biological
indicators. Serving the healthcare industry throughout
the United States and Canada since 1986, we have
thousands of satisfied customers.
§
We
have on-line test
results allowing you to access your results at
your convenience! Your Sterilizer Test Report (STR) is
posted
on-line upon completion
of culturing, offering minimum turn-around time.
§
We
have 24-hour test results for Steam sterilizers!
§
We
have a comprehensive Glossary of Terms related to the
sterile processing area (scroll below to view the
Glossary). This is invaluable information, assisting
you with this important area of your facility.
ATS,
Inc. now stocks sterilization pouches, sterilizer
cleaners, chemical indicator products, sterilizers (new
and used), ultrasonic cleaners, water distillers, and
more! (see
Supplies).
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